The prognostic significance of ING4 expression on gastric gastrointestinal stromal tumors by immunohistochemistry

ŞAHİN S., EKİNCİ Ö., Seckin S., DURSUN A.

ANNALI ITALIANI DI CHIRURGIA, cilt.88, sa.4, ss.311-317, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 88 Sayı: 4
  • Basım Tarihi: 2017
  • Dergi Adı: ANNALI ITALIANI DI CHIRURGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.311-317
  • Anahtar Kelimeler: Clinicopathological features, Gastrointestinal stromal tumor, ING4, Immunohistochemistry, SUPPRESSOR GENE, DOWN-REGULATION, POOR-PROGNOSIS, DIAGNOSIS, FEATURES, DOG1, PROLIFERATION, CARCINOMAS, SURVIVAL, GROWTH
  • Gazi Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Inhibitor of growth 4 (ING4) is a novel tumor suppressor gene that is reported to be down-regulated in various tumors including gastrointestinal stromal tumors (GISTs) originated from different locations, recently. Herein, we aimed to evaluate ING4 expression and its prognostic significance on gastric GISTs in order to add further data to the current literature.