Selenium levels and glutathione peroxidase activities in patients with acute myocardial infarction


Bor M., Cevik C., Uslu İ., Guneral F., Duzgun E.

ACTA CARDIOLOGICA, vol.54, no.5, pp.271-276, 1999 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 5
  • Publication Date: 1999
  • Journal Name: ACTA CARDIOLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.271-276
  • Keywords: myocardial infarction, selenium, glutathione peroxidase, erythrocyte, plasma, urine, SERUM SELENIUM, DEFICIENCY, PLASMA, HEART, ASSOCIATION, REPERFUSION, DEFENSES, ISCHEMIA, DISEASE, CELLS
  • Gazi University Affiliated: No

Abstract

Objective - Selenium (Se) is part of the enzyme glutathione peroxidase (GSH-Px) that plays an important role in the antioxidant defence of the body, including the myocardium, against the deleterious actions of free radicals and lipid peroxides. In order to evaluate the Se status and the GSH-Px activity in ischaemic heart disease, plasma, erythrocyte and urinary Se concentrations together with plasma and erythrocyte GSH-Px activities were determined in 27 patients diagnosed as acute myocardial infarction (AMI). The control group consisted of 24 age-matched healthy individuals.