The condition of the ambient air must be continuously checked to detect hazardous gas leakage and ensure the safety of employees in hazardous gas production and storage areas. Detection and elimination of hazardous gas leaks can be done with various complex measurement, safety, and disposal systems. These measurement systems consist of different types of sensor and require control and monitoring system. This leads to high investment and operating costs. In this study, semi-continuous measurement system automation with a single set of sensors working by taking air samples from different points over specific periods has been designed to reduce investment, operation, and maintenance repair costs. In the design, the measurement points are divided into zones and codes in the automation system. Thus, it is aimed to keep a constant record of what the air sample is coming from and what its content is. As a result, it has been determined that it is possible to establish a measurement and automation system similar to existing hazardous gas measurement systems with less investment and operating costs. The proposed automation system has been applied in the industrial storage area. In addition, a cost analysis has been performed and compared with conventional systems.