Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1 alpha, CXCR4 and CA9 in colorectal carcinoma

Saka B., EKİNCİ Ö., DURSUN A., AKYÜREK N.

PATHOLOGY RESEARCH AND PRACTICE, vol.213, no.7, pp.783-792, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 213 Issue: 7
  • Publication Date: 2017
  • Doi Number: 10.1016/j.prp.2017.04.001
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.783-792
  • Keywords: Colorectal carcinoma, Prognosis, Survival, HIF-1 alpha, CA9, CXCR4, CARBONIC-ANHYDRASE-IX, HYPOXIA-INDUCIBLE FACTOR-1-ALPHA, ENDOTHELIAL GROWTH-FACTOR, CHEMOKINE RECEPTOR CXCR4, CANCER STATISTICS, RECTAL-CANCER, CHEMOTHERAPY, MARKER, CHEMORADIOTHERAPY, MICROENVIRONMENT
  • Gazi University Affiliated: Yes

Abstract

Objective: To investigate the immunohistochemical expressions of HIF-1 alpha, CA9 and CXCR4 in resected human CRC specimens in relation to clinicopathologic and prognostic variables.