Akademik Veri Yönetim Sistemi
INNOVATIVE APPROACHES IN CANCER DIAGNOSIS AND TREATMENT, ss.38-43, 2024 (SCI-Expanded)
Cancer cells have a dynamic cross-talk between tumor microenvironment and cancer cells. This communication is essential in reprogramming the recipient cell and/or microenvironments. Exosomes are a subset of extracellular vesicles that act as multi-molecular messengers by transferring exosomal cargo biomolecules, including proteins,lipids, DNA, mRNAs, and non-coding RNAs. The role of exosomes is dynamic and specific to cancer type and stage. Cancer-derived exosomes are pivotal in regulating tumor growth, angiogenesis, metastasis, drug resistance, and spread in recipient cells. As a result, in this chapter, we attempted to summarize how cancer-derived exosomes induce the initiation and progression of cancer by epigenetically reprogramming the recipient cell and microenvironments.