Synthesis and antimicrobial activity of 1,4-diaryl-2-azetidinones

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Güner V., Yıldırır S., Özçelik B., Abbasoğlu U.

FARMACO, cilt.2, sa.55, ss.147-150, 2000 (SCI-Expanded)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2 Sayı: 55
  • Basım Tarihi: 2000
  • Dergi Adı: FARMACO
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.147-150
  • Gazi Üniversitesi Adresli: Evet

Özet

Cycloaddition of substituted 4,4-benzylidene–anilines to in situ prepared dichloroketenes in the presence of dichloroacetyl chloride and triethylamine affords a variety of 2-azetidinones. All the compounds were characterized by IR and 1H NMR. Their antimicrobial activity, against Gram(+) and Gram(−) bacteria and fungi, was tested.