Rocuronium-Sugammadex Decreases the Severity of Post-Electroconvulsive Therapy Agitation


Postaci A., Tiryaki C., YANARDAĞ R., Ornek D., Kalyoncu M., DİKMEN B.

JOURNAL OF ECT, vol.29, no.1, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1097/yct.0b013e31825de0de
  • Journal Name: JOURNAL OF ECT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Gazi University Affiliated: No

Abstract

A 51-year-old male patient with a diagnosis of refractory major depressive disorder and unresponsive to antidepressants underwent 8 sessions of electroconvulsive therapy (ECT) every 48 hours. Succinylcholine was used for muscle relaxation until the sixth ECT session, and midazolam was administered for severe emergence agitation that recurred after each session. In the sixth ECT session, rocuronium, 0.4 mg/kg, was used for muscle relaxation and sugammadex, 2 mg/kg, for reversal of muscle paralysis. Subsequently, a clear decrease in post-ECT agitation was observed. We suggest that this combination might be a safe and effective alternative to succinylcholine for post-ECT agitation.