Inter-individual Variation in the After-effect of Paired Associative Stimulation can be Predicted From Short-interval Intracortical Inhibition With the Threshold Tracking Method


Murase N., Cengiz B., Rothwell J. C.

BRAIN STIMULATION, vol.8, no.1, pp.105-113, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1016/j.brs.2014.09.010
  • Journal Name: BRAIN STIMULATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.105-113
  • Keywords: Paired associative stimulation, Short-interval intracortical inhibition, Variability, I-wave, Short-latency afferent inhibition, HUMAN MOTOR CORTEX, LONG-TERM POTENTIATION, CORTICAL PLASTICITY, STIMULUS-INTENSITY, 2 PHASES, EXCITABILITY, FACILITATION, INDUCTION, REPRODUCIBILITY, CONTRACTION
  • Gazi University Affiliated: Yes

Abstract

Background: Paired associative stimulation (PAS), which is used to test a long term potentiation (LTP)-like effect, involves repeated pairing of peripheral somatosensory input with transcranial magnetic stimulation (TMS) given 25 ms later over M1 (PAS(25)). The effect is usually quantified as an increase in amplitude of motor evoked potentials evoked by single pulse TMS. However, the effect varies greatly between individuals.