Akademik Veri Yönetim Sistemi
Portuguese journal of cardiac thoracic and vascular surgery, cilt.30, sa.1, ss.31-36, 2023 (Scopus)
Objectives: In recent years, a correlation between prognosis of various cancers and inflammation has been emphasized
in many studies. Here, we have investigated whether preoperative serum uric acid levels, albumin levels, and uric acid to
albumin ratio predict lymph node metastasis in non-small cell lung cancer treated surgically by VATS.
Methods: The medical records of patients who underwent VATS lobectomy/segmentectomy for non-small cell lung
cancer between January 2015 and December 2020, were reviewed retrospectively. Groups with and without lymph node
metastasis and high and low groups with high and low uric acid to albumin ratio were created. Pearson chi-square test was
used to investigate whether any significant correlation between the groups existed.
Results: A total of 115 patients were included in the study. Lymph node metastasis in N1 and N2 stations was detected
in 11 and 18 patients, respectively. There was a statistically significant correlation between lymph node metastasis and high
uric acid levels (p=0.008, OR: 3.2) and high uric acid to albumin ratio (p=0.03, OR: 2.6)..
Conclusions: Preoperative serum uric acid and uric acid to albumin ratio can predict the lymph node metastasis in
non-small cell lung cancer treated surgically by video assisted thoracic surgery.