Impact of prohepcidin levels and iron parameters on early post-transplantation toxicities

Aki, Sahika; PAŞAOĞLU, HATİCE; YEGİN, ZEYNEP; Suyani, Elif; Demirtas, CANAN; ÖZKURT, ZÜBEYDE; Yagci, ABDULLAH; Sucak, Gulsan

doi:10.1179/102453311x13085644680023

Impact of prohepcidin levels and iron parameters on early post-transplantation toxicities

Aki S. Z., PAŞAOĞLU H., YEGİN Z. A., Suyani E., Demirtas C., ÖZKURT Z. N., ...Daha Fazla

HEMATOLOGY, cilt.16, sa.5, ss.284-290, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 16 Sayı: 5
Basım Tarihi: 2011
Doi Numarası: 10.1179/102453311x13085644680023
Dergi Adı: HEMATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.284-290
Anahtar Kelimeler: Haematopoietic stem cell transplantation, Prohepcidin, Iron overload, Early post-transplantation toxicities, STEM-CELL TRANSPLANTATION, BONE-MARROW-TRANSPLANTATION, NONTRANSFERRIN-BOUND IRON, HIGH-DOSE CHEMOTHERAPY, SERUM FERRITIN, FREE-RADICALS, OVERLOAD, HEPCIDIN, LIVER, THALASSEMIA
Gazi Üniversitesi Adresli: Evet

Özet

Objective: Recent reports show the adverse impact of pre-transplantation iron overload on the outcome of haematopoietic stem cell transplantation (HSCT). We studied the pre-transplantation serum iron (SI) parameters including prohepcidin levels - a regulatory peptide of systemic iron homeostasis - and their role in early post-transplantation toxicities in allogeneic HSCT recipients.