Akademik Veri Yönetim Sistemi
Fabad Journal of Pharmaceutical Sciences, cilt.50, sa.2, ss.493-512, 2025 (Scopus)
The incidence of neurological illnesses has recently escalated globally, posing significant challenges for both individuals and their families. The ineffectiveness of the majority of existing chemical medications for treating these ailments has prompted researchers to explore other therapeutic approaches. Recently, plant-derived exosome-like nanovesicles (PELNs) have garnered attention from researchers owing to their industrial applicability, low cellular toxicity, excellent biocompatibility, and acceptance by the immune system. This paper presents an overview of PELNs and discusses their isolation and characterization methodologies. The mechanisms of action of PELNs in both in vivo and in vitro brain illness models will be examined. Ultimately, we will present information on the obstacles linked to the utilization of PELNs and their prospective positioning concerning neurological disorders.