Value of the New Bone Classification System in Pediatric Renal Osteodystrophy


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BAKKALOĞLU EZGÜ S. A. , Wesseling-Perry K., Pereira R. C. , Gales B., Wang H., Elashoff R. M. , ...More

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, vol.5, no.10, pp.1860-1866, 2010 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 10
  • Publication Date: 2010
  • Doi Number: 10.2215/cjn.01330210
  • Journal Name: CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1860-1866

Abstract

Background and objectives: Although lesions of renal osteodystrophy have traditionally been defined by bone turnover, alterations in skeletal mineralization and volume are also prevalent and may contribute to significant morbidity in patients with chronic kidney disease (CKD). The study presented here was undertaken to compare the traditional spectrum of renal osteodystrophy defined by bone turnover to a new classification system that includes T (turnover), M (mineralization), and V (volume) and to determine the value of biochemical parameters as predictors of specific TMV lesions.