Malignant pleomorphic adenoma (malignant mixed tumor) of the trachea: a case report and review of the literature

Demirag F., Topcu S., Kurul C. , Memis L., Altinok T.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, cilt.260, sa.2, ss.96-99, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 260 Konu: 2
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1007/s00405-002-0515-5
  • Sayfa Sayıları: ss.96-99


A case of malignant mixed tumor of the trachea in a 56-year-old man is described. His tumor was removed by segmental tracheal resection, and end-to-end anastomosis was performed. Histologically, the tumor was characterized by a biphasic composition showing admixtures of epithelial elements in varying proportions; these were cytologically atypical with prominent mitotic figures. However, stromal elements were osteoid and mixoid with a benign appearance. The patient had no evidence of disease in the head and neck region and had no history of previous surgery for a salivary gland tumor. These findings were interpreted as indicative of malignant pleomorphic adenoma of the trachea.