Simultaneous onset of pemphigus vulgaris in two Turkish siblings.

Kavak A., Aydogan I., Gonen S.

The Journal of dermatology, cilt.32, sa.3, ss.186-8, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 3
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1346-8138.2005.tb00742.x
  • Dergi Adı: The Journal of dermatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.186-8
  • Gazi Üniversitesi Adresli: Evet

Özet

The etiology of pemphigus vulgaris is still unknown. Reported familial cases are indicators of a genetic aspect of the disease. We report a brother and sister with simultaneous onset of pemphigus vulgaris. The class II antigens, HLA DRB1*04 and DQB1*03 were detected in both patients. The oral mucosa was affected in one them. Elevation of transaminase levels due to azathioprine therapy was observed in these two cases.