Simultaneous onset of pemphigus vulgaris in two Turkish siblings.
The Journal of dermatology, cilt.32, sa.3, ss.186-8, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 3
- Basım Tarihi: 2005
- Doi Numarası: 10.1111/j.1346-8138.2005.tb00742.x
- Dergi Adı: The Journal of dermatology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.186-8
- Gazi Üniversitesi Adresli: Evet
Özet
The etiology of pemphigus vulgaris is still unknown. Reported familial cases are indicators of a genetic aspect of the disease. We report a brother and sister with simultaneous onset of pemphigus vulgaris. The class II antigens, HLA DRB1*04 and DQB1*03 were detected in both patients. The oral mucosa was affected in one them. Elevation of transaminase levels due to azathioprine therapy was observed in these two cases.