Diagnostic value of neopterin during neutropenic fever and determination of disease activity in childhood leukemias

Belen F. B. , KOÇAK Ü. , Albayrak M., KAYA Z. , Gursel T.

DISEASE MARKERS, cilt.33, sa.1, ss.11-18, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Konu: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1155/2012/474085
  • Sayfa Sayıları: ss.11-18


Neopterin, a pteridine group compound that is secreted from macrophages is shown to be increased in adult leukemia; however there are few studies in childhood leukemia. This study aimed to investigate neopterin levels during childhood leukemia treatment and neutropenic fever episodes for the possibility of using as a marker for disease activity and differentiation of infections.