Parechovirus infection mimicking bacterial sepsis in an infant Bir infantta bakteriyel sepsisi taklit eden parekovirüs enfeksiyonu

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Tokmak D. N., Yalçınkaya R., Gülenç N., Öz F. N., Kaman A., AYDIN TEKE T., ...More

Cocuk Enfeksiyon Dergisi, vol.15, no.1, 2021 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.5578/ced.20219925
  • Journal Name: Cocuk Enfeksiyon Dergisi
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Keywords: Infant, Meningitis, Parechovirus, Sepsis
  • Gazi University Affiliated: Yes

Abstract

Human parechoviruses (HPeV) are responsible for gastrointestinal and respiratory system infections which are seen mostly in the first year of life. It is known that HPeV may cause sepsis like syndrome and meningo-encephalitis in neonates and infants. Although the prognosis of central nervous system infections caused by HPeV are suggested to be quite good and similar to enteroviruses, there are reports of severe cases which cause encephalitis and neurological sequels. The use of polymer-ase chain reaction (PCR) test in diagnosis may reduce antibiotic use and length of hospital stay. There are no specific antiviral agents for treat-ment. This is a report of a 38-day-old febrile infant admitted with a sep-sis-like clinical condition and diagnosed with HPeV meningitis through cerebrospinal fluid PCR test.