The Development of Spectrophotometric and Validated Stability-Indicating RP-HPLC Methods for Simultaneous Determination of Ephedrine HCL, Naphazoline HCL, Antazoline HCL, and Chlorobutanol in Pharmaceutical Pomade Form


Dindar C. K. , Erkmen C., Uslu B., Goger N.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, vol.23, no.10, pp.1090-1099, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 10
  • Publication Date: 2020
  • Doi Number: 10.2174/1386207323666200720101835
  • Journal Name: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
  • Journal Indexes: Science Citation Index Expanded, Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1090-1099

Abstract

Background: Allergic rhinitis, acute nasal congestion and sinusitis are one of the most common health problems and have a major effect on the quality of life. Several medications are used to improve the symptoms of such diseases in humans. Pharmaceutical pomade form containing Ephedrine (EPD) HCl, Naphazoline (NPZ) HCl, Antazoline (ANT) HCl, and Chlorobutanol (CLO) is one of them.