Atıf İçin Kopyala
ÖZEN A. O., Kasap N., Vujkovic-Cvijin I., Apps R., Cheung F., Karakoc-Aydiner E., ...Daha Fazla
NATURE IMMUNOLOGY, cilt.22, sa.2, ss.128-151, 2021 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
22
Sayı:
2
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Basım Tarihi:
2021
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Doi Numarası:
10.1038/s41590-020-00830-z
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Dergi Adı:
NATURE IMMUNOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
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Sayfa Sayıları:
ss.128-151
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Gazi Üniversitesi Adresli:
Evet
Özet
CHAPLE disease is a lethal syndrome caused by genetic loss of the complement regulatory protein CD55. Lenardo, Ozen and their colleagues report that blockade of C5 complement activation in a small cohort of pediatric patients with CHAPLE disease reduced gastrointestinal pathology and restored their immunity and growth.