Increased accumulation of TI-201 in monostotic Paget's disease of the patella - Evaluation with quantitative analysis


Abamor E., Kitapci M., Cila E., Gokcora N., Uluoglu O.

CLINICAL NUCLEAR MEDICINE, vol.26, no.7, pp.615-618, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 7
  • Publication Date: 2001
  • Doi Number: 10.1097/00003072-200107000-00008
  • Journal Name: CLINICAL NUCLEAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.615-618
  • Keywords: bone, Paget disease, patella, TI-201 MDP, BONE, TL-201, DIAGNOSIS, LESIONS
  • Gazi University Affiliated: No

Abstract

Monostotic Paget's disease of the patella was detected with Tc-99m MDP and Tl-201 scans, Diffuse intense uptake of MDP in the left patella was observed on the blood-pool and late phases of the bone scan. Tl-201 imaging was performed to differentiate a malignant process and showed diffuse marked accumulation at the same site, Semiquantitative analysis of the patella region on both Tc-99m MDP and Tl-201 scans did not support a diagnosis of cancer. Radiographs showed the features of Paget's disease of the bone. Findings of a pathologic evaluation were compatible with the diagnosis of osteitis deformans. This case represents the unusual skeletal involvement of monostotic Paget's disease of the bone in the patella, Tl-201 accumulation in the Paget's lesion was suggested to be caused by increased metabolic activity of the lesion but was not indicative of a malignant process.