Akademik Veri Yönetim Sistemi
12th International Hippocrates Congress On Medical and Health Sciences, 1 - 02 Eylül 2023
Abstract: Cerebrovascular disease is one of the causes of secondary parkinsonism. It is hard to
differentiate vascular parkinsonism with an asymmetrical onset from idiopathic Parkinson’s disease
(PD). New methods are needed to increase the accuracy of the diagnosis. Transcranial Doppler
Ultrasound is a reliable method to evaluate cerebral hemodynamic parameters. Methods: Mean blood
flow velocity (Vm), peak systolic velocity, resistivity index (RI) and pulsatility index (PI) of extracranial
segment of internal carotid artery (ICA), middle cerebral artery (MCA), anterior cerebral artery (ACA),
vertebral artery (VA) and basilar artery (BA) were measured in 19 PD, 12 VP patients and 20 healthy
volunteers. Results: Lower Vm values and higher RI and PI values were measured in VP patients in
ICA, MCA, ACA, VA and BA compared to the control group. Lower Vm and higher RI and PI values
were measured in ACA, ICA and VA in VP patients compared to PD patients. Conclusion: Higher PI
and RI values and lower Vm values in both extracranial and intracranial arteries showed that an increase
in distal vascular resistance and a decrease in cerebral blood flow were associated with VP. A more
prominent hemodynamic alterations were observed in ACA compared to MCA in VP patients. TCD
studies in larger populations, in which a cut-off value for PI for each artery is determined may help
differentiating VP from PD.