Efficiency of L-arginine enriched cardioplegia and non-cardioplegic reperfusion in ischemic hearts

Kiziltepe, U; Tunctan, B; Eyileten, ZB; Sirlak, M; Arikbuku, M; Tasoz, R; Uysalel, A; Ozyurda, U

doi:10.1016/j.ijcard.2003.08.015

Efficiency of L-arginine enriched cardioplegia and non-cardioplegic reperfusion in ischemic hearts

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Kiziltepe U., Tunctan B., Eyileten Z., Sirlak M., Arikbuku M., Tasoz R., ...More

INTERNATIONAL JOURNAL OF CARDIOLOGY, vol.97, no.1, pp.93-100, 2004 (SCI-Expanded)

Publication Type: Article / Article
Volume: 97 Issue: 1
Publication Date: 2004
Doi Number: 10.1016/j.ijcard.2003.08.015
Journal Name: INTERNATIONAL JOURNAL OF CARDIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.93-100
Keywords: nitric oxide, coronary artery bypass surgery, ischemia/reperfusion, cardioplegia, NITRIC-OXIDE, MYOCARDIAL-ISCHEMIA, PROTECTION, PEROXYNITRITE, INJURY, ARREST
Gazi University Affiliated: No

Abstract

Objective: Endothelial dysfunction with decreased nitric oxide (NO) levels has been implicated on reperfusion injury. Although L-arginine has been shown to diminish reperfusion injury in in vitro studies, clinical studies were very limited.