Efficiency of L-arginine enriched cardioplegia and non-cardioplegic reperfusion in ischemic hearts

Kiziltepe U., Tunctan B., Eyileten Z., Sirlak M., Arikbuku M., Tasoz R., ...More

INTERNATIONAL JOURNAL OF CARDIOLOGY, vol.97, no.1, pp.93-100, 2004 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 97 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1016/j.ijcard.2003.08.015
  • Journal Name: INTERNATIONAL JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.93-100
  • Keywords: nitric oxide, coronary artery bypass surgery, ischemia/reperfusion, cardioplegia, NITRIC-OXIDE, MYOCARDIAL-ISCHEMIA, PROTECTION, PEROXYNITRITE, INJURY, ARREST

Abstract

Objective: Endothelial dysfunction with decreased nitric oxide (NO) levels has been implicated on reperfusion injury. Although L-arginine has been shown to diminish reperfusion injury in in vitro studies, clinical studies were very limited.