High Dose Cotinine may Induce Neural Tube Defects in a Chick Embryo Model


Dalgic A., Armagan E., Helvacioblu F., Okay O., Daglioglu E., Take G., ...Daha Fazla

TURKISH NEUROSURGERY, cilt.19, sa.3, ss.224-229, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 3
  • Basım Tarihi: 2009
  • Dergi Adı: TURKISH NEUROSURGERY
  • Sayfa Sayıları: ss.224-229

Özet

AIM: Nicotine is a well-known agent among 4000 chemicals in cigarettes. About 70 to 80% of nicotine is converted to cotinine, a major metabolite. The aim of the present study is to investigate the effect of cotinine on neural tube development in a chick embryo model.