A Modified Perfluoro-n-octane-Assisted Autologous Internal Limiting Membrane Transplant for Failed Macular Hole Reintervention: A Case Series

ÖZDEK Ş. , Baskaran P., KARABAŞ V. L. , Neves P. P.

OPHTHALMIC SURGERY LASERS & IMAGING RETINA, cilt.48, sa.5, ss.416-420, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Konu: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3928/23258160-20170428-08
  • Sayfa Sayıları: ss.416-420


The authors describe a modified perfluoro- n-octane (PFO)-assisted autologous internal limiting membrane (ILM) transplantation technique for macular hole (MH) reintervention and present results from a series of 11 patients. The authors harvested a free ILM flap and transplanted it into the MH under a PFO bubble. The time at which PFO is injected, the extent of coverage of PFO, and the sequence of fluid-air exchange (FAE) are crucial to overcome previously described technical difficulties of relieving the flap from forceps, stabilizing the flap into the MH, and prevention of flap dislodgement during FAE. A successful U-shaped closure was observed in 10 of 11 cases (90.9%). One case (9.1%) showed flat open closure. The postoperative visual gain was statistically significant (P =.01).