Evaluation of the skeletal defects caused by caffeine and sodium salicylate in mouse embryo

Erdogan D., Peker T. V., Kadioglu D.

JOURNAL OF NEUROLOGICAL AND ORTHOPAEDIC MEDICINE AND SURGERY, vol.16, no.4, pp.214-221, 1996 (SCI-Expanded) identifier


Although drug preparations containing acetyl salicylic acid and caffeine are based commonly nowadays, they are considered to be teratogenic on the basis of animal experiments. We therefore investigated skeletal anomalies in fetuses caused by combinations containing sodium salicylate, caffeine, and both administered to mice in the critical period of gestation.