Akademik Veri Yönetim Sistemi
11. Ulusal ve 4. Uluslararası Hidatidoloji Kongresi, Edirne, Türkiye, 2 - 04 Ekim 2024, ss.179-180
Objective: Cystic echinococcosis (CE) is a zoonotic infection caused by the larval form of Echinococcus granulosus (E. granulosus ). Although imaging methods are widely used to diagnose this infection, serological diagnosis greatly supports radiological diagnosis, post-treatment patient follow-up, and differential diagnosis. This study aimed to retrospectively evaluate E. granulosus -specific antibodies in serum samples sent to Gazi University Medical Faculty Hospital Medical Microbiology Laboratory with a preliminary diagnosis of CE using the indirect hemagglutination (IHA) test. Materials and Methods: Serum samples of 887 patients with a preliminary diagnosis of CE from various clinics were studied and evaluated by the recommendations of the manufacturers using the IHA (Siemens Cellognosts, Germany; ELI.H.A Echinococcus, France) method between January 2020 and August 2024. According to the Siemens Cellognosts IHA test procedure, values equal to or above 1/256 and according to the ELI.H.A Echinococcus IHA test procedure, values equal to or above 1/320 were considered positive. In addition, statistical analysis of socio-demographic characteristics such as gender and age was performed. Results: Of the patients included in the study, 487 (55%) belonged to females and 400 (45%) to males. The patients were between 1-95 years of age, and the mean age was 42. Of the 887 serum samples in the study, 784 (88.3%) were negative, and 103 (11.7%) were positive for E. granulosus antibodies. Seropositivity was most frequently seen in patients in the 19-39 and 40-60 age groups. A statistically significant difference was found in the under-40 age groups for anti-E. granulosus antibodies (p=<0.001) (Table 1). Conclusion: Cystic echinococcosis continues to be a public health problem in cases presenting to our hospital, as it is in TÜRKİYE in general. Since the clinical findings of CE can develop over many years and can be confused with many other diseases (non-CH cysts, abscess, tumour, haemangioma, hepatocellular carcinoma, cirrhosis, etc.), it would be helpful to evaluate the clinical, radiological and microbiological findings together in a multidisciplinary manner.