Cheap, Suitable, Predictable and Manageable Nanoparticles for Drug Delivery: Quantum Dots

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Degim I. T., Kadioglu D.

CURRENT DRUG DELIVERY, cilt.10, sa.1, ss.32-38, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.2174/1567201811310010006
  • Dergi Adı: CURRENT DRUG DELIVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.32-38
  • Anahtar Kelimeler: Dexketoprofen, ketoprofen, kuantum dots, penetration, transdermal, ZnO, ZINC-OXIDE NANOPARTICLES, ANTIBACTERIAL ACTIVITIES, CARBON NANOTUBES, INTRACELLULAR PH, CANCER-CELLS, ZNO, SURFACE, NANOTECHNOLOGY, NANOMATERIALS, PERMEABILITY
  • Gazi Üniversitesi Adresli: Evet

Özet

Recently ZnO quantum dots are reported to be very promising for drug delivery. It has also been reported that adsorptive material can deliver drug molecules by simple adsorption and they release the drug at site of action by subsequent desorption. This has been shown for carbon nanotubes and some other hydrophobic molecules for transdermal applications in the literature. Therefore it was aimed to find the effect of ZnO quantum dots on transdermal penetrations of selected model drug molecules (ketoprofen and dexketoperofen). Drug coated ZnO quantum dots were found to increase transdermal penetration of ketoprofen and dexketoprofen through rat skin.