The role of IFIH1 gene rs1990760 and rs2111485 single-nucleotide polymorphisms in generalized vitiligo predisposition

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Onan D., Yorulmaz A., EZGÜ F. S., HAYRAN K. M., Kulcu S., Artuz R. F., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.49, sa.1, ss.206-211, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3906/sag-1808-63
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.206-211
  • Anahtar Kelimeler: Vitiligo, single nucleotide polymorphism, genes, GENOME-WIDE ASSOCIATION, RIG-I, RISK LOCI, VARIANTS, RESPONSES, PROTECT, MDA5
  • Gazi Üniversitesi Adresli: Evet

Özet

Background/aim: Interferon-induced helicase (IFIH1) is a gene locus that has been recently defined as a candidate for susceptibility to generalized vitiligo (GV). The objectives of this study were to assess the association of IFIH1 gene, rs2111485, and rs1990760 single-nucleotide polymorphisms (SNP) with susceptibility to GV and the autoimmune diseases accompanying CV.