The role of IFIH1 gene rs1990760 and rs2111485 single-nucleotide polymorphisms in generalized vitiligo predisposition

Creative Commons License

Onan D., Yorulmaz A., EZGÜ F. S., HAYRAN K. M., Kulcu S., Artuz R. F., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.49, sa.1, ss.206-211, 2019 (SCI-Expanded, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3906/sag-1808-63
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.206-211
  • Anahtar Kelimeler: Vitiligo, single nucleotide polymorphism, genes, GENOME-WIDE ASSOCIATION, RIG-I, RISK LOCI, VARIANTS, RESPONSES, PROTECT, MDA5
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Gazi Üniversitesi Adresli: Evet

Özet

Background/aim: Interferon-induced helicase (IFIH1) is a gene locus that has been recently defined as a candidate for susceptibility to generalized vitiligo (GV). The objectives of this study were to assess the association of IFIH1 gene, rs2111485, and rs1990760 single-nucleotide polymorphisms (SNP) with susceptibility to GV and the autoimmune diseases accompanying CV.