Effects of Topical Cova (TM), Tisseel (R) and Adcon (R) Gel Application on the Development of Spinal Peridural Fibrosis: An Experimental Study in Rats

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Kazanci A., Gurcan O., Gurcay A. G., Onder E., Kazanci B., YAMAN M. E., ...Daha Fazla

TURKISH NEUROSURGERY, cilt.27, sa.6, ss.962-968, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5137/1019-5149.jtn.16809-15.1
  • Dergi Adı: TURKISH NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.962-968
  • Gazi Üniversitesi Adresli: Hayır

Özet

AIM: Leptomeningeal adhesions and fibrosis in the spinal peridural space are the most common causes of post-laminectomy syndrome. Fibrin sealant agents and membrane barriers are commonly used for hemostasis and sealing purposes in spinal surgery. Peridural fibrosis may be a risk of the usage of these topical agents. In this study, we aimed to compare the effects of Cova (TM), Tisseel (R) and Adcon (R) Gel on the development of spinal peridural fibrosis in the experimental rat model.