The effect of vitamin E on acute skin reaction caused by radiotherapy

Dirier A., Akmansu M., Bora H., Gurer M.

CLINICAL AND EXPERIMENTAL DERMATOLOGY, cilt.32, sa.5, ss.571-573, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Konu: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1365-2230.2007.02452.x
  • Sayfa Sayıları: ss.571-573


Ionizing radiation affects healthy organs and tissues as well as diseased tissues during radiation therapy. Skin reactions varying from acute erythema to necrosis can be seen. It has been found that vitamin E can prevent mutagenic and/or carcinogenic effects of ionizing radiation in both animals and cell cultures. This study investigated the preventative effect of antioxidant vitamin E on irradiation-induced acute skin reactions. No protective effect of vitamin E was demonstrated. It is possible that the vehicle induced free radical exposure in the irradiated skin.