The effect of vitamin E on acute skin reaction caused by radiotherapy

Dirier, A.; Akmansu, MÜGE; Bora, HÜSEYİN; Gurer, M.

doi:10.1111/j.1365-2230.2007.02452.x

The effect of vitamin E on acute skin reaction caused by radiotherapy

Dirier A., Akmansu M., Bora H., Gurer M.

CLINICAL AND EXPERIMENTAL DERMATOLOGY, sa.5, ss.571-573, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 2007
Doi Numarası: 10.1111/j.1365-2230.2007.02452.x
Dergi Adı: CLINICAL AND EXPERIMENTAL DERMATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.571-573
Gazi Üniversitesi Adresli: Evet

Özet

Ionizing radiation affects healthy organs and tissues as well as diseased tissues during radiation therapy. Skin reactions varying from acute erythema to necrosis can be seen. It has been found that vitamin E can prevent mutagenic and/or carcinogenic effects of ionizing radiation in both animals and cell cultures. This study investigated the preventative effect of antioxidant vitamin E on irradiation-induced acute skin reactions. No protective effect of vitamin E was demonstrated. It is possible that the vehicle induced free radical exposure in the irradiated skin.