Localized Castleman's disease and nephrotic syndrome not responsive to resection plus colchicine therapy

Derici Ü., Arinsoy T., Ataoglu O., Bali M., Eroglu A., Goker B., ...More

ANNALS OF HEMATOLOGY, vol.81, no.7, pp.399-401, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 81 Issue: 7
  • Publication Date: 2002
  • Doi Number: 10.1007/s00277-002-0486-z
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.399-401
  • Keywords: nephrotic syndrome, Castleman's disease, amyloidosis, colchicine, LYMPH-NODE HYPERPLASIA, RENAL AMYLOIDOSIS, SECONDARY
  • Gazi University Affiliated: Yes


We describe one patient with localized Castleman's disease (CID) of the mixed hyaline vascular and plasma cell type located at the mesentery of the small bowel, associated with systemic amyloidosis and nephrotic syndrome. A true nephrotic syndrome has rarely been reported in patients with CID. In the literature, it has been suggested that clinical and laboratory manifestations generally improved after surgical resection of the tumor. However, in our case, clinical and laboratory findings did not regress after operation followed by colchicine therapy.