Life-threatening Agranulocytosis, Anemia, and Plasmacytosis After Dipyrone Use for Fever in a Child

Isik M., KAYA Z. , Belen F. B. , Aktas A. T. , TEZER H. , Gursel T.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.36, sa.1, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Konu: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1097/mph.0000000000000079
  • Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Özet

Dipyrone or metamizole Na (Novalgin) is commonly used as an antipyretic, analgesic, and spasmolytic agent in some parts of the world; however, it is banned in developed countries because of severe side effects. Here we present a case of a 4-year-old boy who developed life-threatening agranulocytosis, anemia, and marked plasmacytosis in his bone marrow after dipyrone use for fever, which resolved with steroid therapy.