Akademik Veri Yönetim Sistemi
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, sa.2, ss.31-36, 2014 (ESCI)
Evolution is being investigated with the aid of today's technological advances. Evolutionary biology researches directly or indirectly may affect today and tomorrow. When evolution is mentioned, even at first Darwin's Evolutionary Theory and phylogenetic approaches that depend on organisms' morphological features come to mind, there are also hypotheses that see mutation and genetic drift as the genetic diversity resource in populations. Proofs that support evolution vary from rocks and bones to molecules. As living organisms' genome sequences and proteins that are involved in common mechanisms are discovered through DNA sequence analysis, it has been answered to these questions in molecular level like what is the origin of the living organisms, which living organism is relative with another, which organisms share the common ancestor. The hypotheses like origin of the life and evolutionary history are not being able to be explained exactly as the hypothesis testing applications can not be performed in the laboratory. In this review, various theories and hypotheses related with molecular evolution are being discussed with proofs that have been obtained by tracking evolution's molecular marks in the light of mechanisms that affect gene and genome evolution.