Recent advances in bioactive 1D and 2D carbon nanomaterials for biomedical applications

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EROL Ö., Uyan I., Hatip M., Yilmaz C., Tekinay A. B., Guler M. O.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, cilt.14, sa.7, ss.2433-2454, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 14 Sayı: 7
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.nano.2017.03.021
  • Dergi Adı: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2433-2454
  • Anahtar Kelimeler: Carbon nanotube, Graphene, Graphene oxide, Biomedical applications, Biocompatibility, MESENCHYMAL STEM-CELLS, SINGLE-WALLED NANOTUBES, GRAPHENE OXIDE, OSTEOGENIC DIFFERENTIATION, ELECTRICAL-STIMULATION, NANOSTRUCTURED CARBON, IN-VITRO, MYOBLAST DIFFERENTIATION, FUNCTIONALIZED GRAPHENE, PHOTOTHERMAL THERAPY
  • Gazi Üniversitesi Adresli: Hayır

Özet

One-dimensional (1D) carbon nanotubes (CNTs) and the two-dimensional (2D) graphene represent the most widely studied allotropes of carbon. Due to their unique structural, electrical, mechanical and optical properties, 1D and 2D carbon nanostructures are considered to be leading candidates for numerous applications in biomedical fields, including tissue engineering, drug delivery, bioimaging and biosensors. The biocompatibility and toxicity issues associated with these nanostructures have been a critical impediment for their use in biomedical applications. In this review, we present an overview of the various materials types, properties, functionalization strategies and characterization methods of 1D and 2D carbon nanomaterials and their derivatives in terms of their biomedical applications. In addition, we discuss various factors and mechanisms affecting their toxicity and biocompatibility. (c) 2017 Elsevier Inc. All rights reserved.