Nanospheres caped Pt(II) and Pt (IV): synthesis and evaluation as antimicrobial and Antifungal Agent


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Öğütçü H., Yetim N. K., Hasanoğlu Özkan E., Eren O., Kaya G., Sarı N., ...Daha Fazla

POLISH JOURNAL OF CHEMICAL TECHNOLOGY, cilt.19, ss.74-80, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1515/pjct-2017-0011
  • Dergi Adı: POLISH JOURNAL OF CHEMICAL TECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.74-80
  • Anahtar Kelimeler: antimicrobial agent, antifungal agent, poly(styrene), caped platinium, TRINUCLEAR PLATINUM COMPLEX, DRUG-DELIVERY, SCHIFF BASES, NANOPARTICLES
  • Gazi Üniversitesi Adresli: Evet

Özet

Antimicrobial and antifungal polymers are gaining the attention of pharmaceutical makers and industrial design. Nanospheres-Polymers attached Platinum(II) / (IV) complexes have been synthesized to investigate antimicrobial activities. Firstly, nanospheres involving Schiff bases were synthesized from (aminomethyl) polystyrene and four substitute salicylaldehyde (2-hydroxy benzaldehyde, 5-fluoro-2-hydroxy benzaldehyde, 5-kloro-2-hydroxy benzaldehyde, 5-bromo-2-hydroxy benzaldehyde). Secondly, polymers attached Platinum(II) / (IV) complexes have been prepared by means of template method. The IR spectra show that the ligands act in a monovalent bidentate fashion all nanospheres involving Schiff bases. Square-planar and octahedral structures are proposed for Pt(II) and Pt(IV), respectively. All these substances have been examined for antibacterial activity against pathogenic strains, and antifungal activity. In particular, Pt(IV) complexes were more potent bactericides than all of the synthesized substances.