Recurrent Sertoli-Leydig cell tumor of ovary in 8-year-old girl

TÜRKYILMAZ Z., KARABULUT R., Ozbakir F., PINARLI F. G. , İNAN M. A. , Oguz A., ...More

SCOTTISH MEDICAL JOURNAL, vol.61, no.1, pp.56-59, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1177/0036933015619297
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.56-59
  • Keywords: Sertoli-Leydig cell tumor, ovary, children, RETIFORM PATTERN


Sertoli-Leydig cell tumors are rare sex cord-stromal neoplasms that account for <0.2% of ovarian tumors. These tumors with a retiform pattern pose difficult diagnostic problems, with the majority of being misinterpreted as serous papillary cystadenocarcinoma and endodermal sinus tumor. We report an 8-year-old female patient presented to our institution with a huge mass and pain in the lower abdomen and recurrence in the 10th months following the first operation. Only four cases of Sertoli-Leydig cell tumors have been reported under age of the eight years in the literature so far. It is difficult to define the stage and the morphology of Sertoli-Leydig cell tumors with retiform pattern in children and chemotherapy or radiotherapy administration is contraversial. However, fertility sparing surgeries should be considered as a first treatment choice on the time of the diagnosis and the recurrence.