Mucoralactone a: An unusual steroid from the liquid culture of mucor plumbeus

Ata A., Conci L. J., Orhan İ.

Heterocycles, vol.68, no.10, pp.2097-2106, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 10
  • Publication Date: 2006
  • Doi Number: 10.3987/com-06-10829
  • Journal Name: Heterocycles
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2097-2106
  • Gazi University Affiliated: Yes


Mucoralactone A (1), a novel steroid, was isolated from the liquid culture of Mucor plumbeus. Its structure was elucidated with the aid of extensive spectroscopic studies. Mucoralactone A (1) has a lactone moiety incorporated in its structure, and exhibited acetylcholinesterase enzyme inhibition activity with an IC50 value of 19 μM and modest antifungal activity against Candida albicans. © 2006 The Japan Institute of Heterocyclic Chemistry.