Mucoralactone a: An unusual steroid from the liquid culture of mucor plumbeus


Ata A., Conci L. J. , Orhan İ.

Heterocycles, cilt.68, sa.10, ss.2097-2106, 2006 (SCI Expanded İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Konu: 10
  • Basım Tarihi: 2006
  • Doi Numarası: 10.3987/com-06-10829
  • Dergi Adı: Heterocycles
  • Sayfa Sayıları: ss.2097-2106

Özet

Mucoralactone A (1), a novel steroid, was isolated from the liquid culture of Mucor plumbeus. Its structure was elucidated with the aid of extensive spectroscopic studies. Mucoralactone A (1) has a lactone moiety incorporated in its structure, and exhibited acetylcholinesterase enzyme inhibition activity with an IC50 value of 19 μM and modest antifungal activity against Candida albicans. © 2006 The Japan Institute of Heterocyclic Chemistry.