Metoclopramide-Induced Dystonic Reaction in an Infant

Tomar-Guneysu S., Derinöz Güleryüz O., Colak O., Fidanci I.

SIGNA VITAE, vol.16, no.1, pp.203-205, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.22514/sv.2020.16.0029
  • Journal Name: SIGNA VITAE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), EMBASE, Veterinary Science Database
  • Page Numbers: pp.203-205
  • Gazi University Affiliated: Yes


Metoclopramide-induced dystonic reaction (MIDR) is a clinical condition that can be seen even in all age groups even in treatment doses. A nine-month-old girl was brought to our emergency department with acute dystonic reaction that occurred after her 2.5-years-old sister gave her a 10 mg/kg metoclopramide tablet two hours before admission to the hospital. Diphenhydramine was given to the patient. One hour later, the patient's clinical findings regressed and patient was hospitalized, and was discharged from the hospital after 66 hours without sequelae. Although metoclopramide-induced dystonic reaction is frequently reported, the number of cases under one year of age is very limited. The case presented in this report is a patient who received a higher drug dose compared to other cases reported in the literature and recovered without sequelae after follow-up. The most important factor resulting in poisoning in children is not arranging the living spaces of the children by the parents. The easiest way to prevent such cases is to educate families on this issue.