Klebsiella oxytoca bacteremia in children: an eight-year single-center experience Çocuklarda Klebsiella oxytoca bakteremisi: Sekiz yıllık tek merkez deneyimi
Cocuk Sagligi ve Hastaliklari Dergisi, cilt.69, sa.1, ss.1-6, 2026 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 69 Sayı: 1
- Basım Tarihi: 2026
- Dergi Adı: Cocuk Sagligi ve Hastaliklari Dergisi
- Derginin Tarandığı İndeksler: Scopus, EMBASE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO)
- Sayfa Sayıları: ss.1-6
- Anahtar Kelimeler: antimicrobial susceptibility, community-onset infection, Gram-negative bacteremia, Klebsiella oxytoca, pediatric bacteremia
- Gazi Üniversitesi Adresli: Evet
Özet
This study aimed to retrospectively evaluate the annual distribution, clinical characteristics, and antimicrobial resistance patterns of Klebsiella oxytoca bacteremia among hospitalized children over an eight-year period. Children aged 1 month to 18 years with monomicrobial K. oxytoca bacteremia between January 2018 and December 2025 were included. Demographic and clinical data, infection onset, outcomes, and antimicrobial susceptibility results were analyzed. A total of 45 patients were identified (median age 92 months; 55% male). Gastrointestinal diseases were the most common comorbidity. Most episodes were community-onset (64.4%). Pediatric intensive care unit admission and mechanical ventilation were required in 24.4% and 15.5% of patients, respectively, and mortality was 4.4%. In conclusion, K. oxytoca is a clinically relevant cause of pediatric bacteremia, with an increasing number of cases observed in recent years. Its predominantly community-onset presentation and high antimicrobial susceptibility support targeted therapy and improved antimicrobial stewardship strategies in children.