No association of polymorphisms in the glutathione S-transferase genes with pre-eclampsia, eclampsia and HELLP syndrome in a Turkish population


Cetin M., Pinarbasi E., Percin F. E. , Akgun E., Percin S., Pinarbasi H., ...Daha Fazla

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, cilt.31, sa.3, ss.236-241, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Konu: 3
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1447-0756.2005.00281.x
  • Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Sayfa Sayıları: ss.236-241

Özet

Aim: There is substantial evidence that genetic factors play a role in pre-eclampsia. The aim of this study was to determine whether genetic variability in the encoding of genes for glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) contributes to individual differences in susceptibility to pre-eclampsia, eclampsia, or hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome).