Serum Sphingosine 1 Phosphate Levels in Patients with and without Coronary Collateral Circulation

Kiziltunc E. , Gok M., Topcuoglu C., Kundi H., Cetin M., Turhan T., ...Daha Fazla

ACTA CARDIOLOGICA SINICA, cilt.34, sa.5, ss.379-385, 2018 (SCI İndekslerine Giren Dergi) identifier identifier


Background: Sphingosine 1 phosphate, an active sphingolipid metabolite, functions in both healthy and diseased cardiovascular systems. It has been reported to play a role in angiogenesis and arteriogenesis in various tissues, which are the proposed mechanisms for the development of coronary collateral circulation. To the best of our knowledge, no data exist regarding serum sphingosine 1 phosphate levels and the presence of coronary collateral circulation in the literature. Thus this study aimed to investigate serum sphingosine 1 phosphate levels in patients with and without coronary collateral circulation.