Severe hypothyroidism caused by hepatic hemangioendothelioma in an infant of a diabetic mother

Guven A., Aygun C., Ince H., Aydin M., PINARLI F. G., Baysal K., ...Daha Fazla

HORMONE RESEARCH, cilt.63, sa.2, ss.86-89, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1159/000083879
  • Dergi Adı: HORMONE RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.86-89
  • Anahtar Kelimeler: hemangioendothelioma, hypothyroidism, newborn and infant, diabetic mother, TYPE-3 IODOTHYRONINE DEIODINASE, HEMANGIOMAS, LIVER, BORN
  • Gazi Üniversitesi Adresli: Hayır

Özet

Hemangioendotheliomas can express type 3 iodothyronine deiodinase and cause severe hypothyroidism. The risk of congenital malformations such as vertebral and cardiac abnormalities in infants of diabetic mothers is higher than babies of healthy women. Here we report an infant of a diabetic mother with hypothyroidism caused by liver hemangioendothelioma. Consumptive hypothyroidism should be an indicator to search for a vascular tumor in infants. Supranormal doses of L-thyroxine might be required for normalization of thyroid function until the tumor involutes or is resected. Copyright (C) 2005 S. Karger AG, Basel.