The importance of serum biglycan levels as a fibrosis marker in patients with chronic hepatitis B

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Ciftciler R., Ozenirler S., Yucel A., Cengiz M., Erkan G., Buyukdemirci E., ...Daha Fazla

JOURNAL OF CLINICAL LABORATORY ANALYSIS, cilt.31, sa.5, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/jcla.22109
  • Dergi Adı: JOURNAL OF CLINICAL LABORATORY ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: biglycan, chronic hepatitis B, liver biopsy, liver fibrosis, non-invasive marker, LIVER FIBROSIS, EXPRESSION, DECORIN, LOCALIZATION
  • Gazi Üniversitesi Adresli: Evet

Özet

BackgroundLiver biopsy is recommended in the majority of patients with chronic viral hepatitis for fibrosis evaluation. Because of the potential risks of liver biopsy, many studies related to non-invasive biomarkers of hepatic fibrosis have been performed. We aimed to assess the diagnostic value of serum biglycan as a non-invasive fibrosis marker in chronic hepatitis B patients.