Establishment of a Primary Pleomorphic Xanthoastrocytoma Cell Line: In Vitro Responsiveness to Some Chemotherapeutics

BAĞRIAÇIK E. Ü., Baykaner M. K., Yaman M., Sivrikaya G., Durdag E., Emmez H., ...Daha Fazla

NEUROSURGERY, cilt.70, sa.1, ss.188-197, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 70 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1227/neu.0b013e3182262c5b
  • Dergi Adı: NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.188-197
  • Anahtar Kelimeler: Anticancer chemotherapy, Brain tumors, Cell culture, Confocal microscopy, OF-THE-LITERATURE, MALIGNANT GLIOMA, CHEMOSENSITIVITY TEST, SURGICAL RESECTION, RESISTANCE ASSAYS, ADVANCED CANCER, TEMOZOLOMIDE, BRAIN, TUMORS, SENSITIVITY
  • Gazi Üniversitesi Adresli: Evet

Özet

BACKGROUND: Anaplastic pleomorphic xanthoastrocytoma is an aggressively growing, malignant, and eventually fatal tumor of the central nervous system. Testing chemotherapeutic drug sensitivity under in vitro conditions would be a useful strategy to determine sensitive or resistant drugs for fatal brain cancers.