Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia


ERDEMOĞLU E., GÜNEY M., Giray S. G. , Take G., Mungan T.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, cilt.145, sa.2, ss.195-199, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 145 Konu: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.ejogrb.2009.04.034
  • Dergi Adı: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
  • Sayfa Sayıları: ss.195-199

Özet

Objective: The effects of metformin on S6K1, which is a crucial effector of mTOR signaling, and on endometrium were studied in a mouse model of endometrial hyperplasia induced by unopposed estradiol or tamoxifen.