Comparison of Oxiplex and Gore-Tex effectivity in an experimental peridural fibrosis model

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Kurt G., Cemil B., Celik B., Durdag E., Erdem O., Ceviker N.

NEUROCIRUGIA, cilt.20, ss.360-366, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20 Konu: 4
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/s1130-1473(09)70155-1
  • Sayfa Sayıları: ss.360-366


Objective. The authors conducted a study to compare the effectiveness of Oxiplex and Gore-tex in preventing postiaminectomy peridural fibrosis in rats. Peridural fibrosis is a common cause of pain in patients undergoing spinal surgery. To prevent scar formation numerous materials and methods have been employed such as non steroidal anti-inflammatory drugs (NSAIDs), Gelfoam, Oxiplex, Gore-tex, carboxymethil cellulose, Adcon-L, autogenous adipose grefting, mitomisin, and radiotherapy have been investigating for a long time, but only moderate success has been obtained.