Effects of Continuous and Intermittent Magnetic Fields on Oxidative Parameters In vivo

Coskun Ş., Balabanli B., Canseven A., Seyhan N.

NEUROCHEMICAL RESEARCH, cilt.34, sa.2, ss.238-243, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s11064-008-9760-3
  • Dergi Adı: NEUROCHEMICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.238-243
  • Anahtar Kelimeler: Magnetic field, Lipid peroxidation, Antioxidant, Nitric oxide, FREE-RADICAL PROCESSES, GAMMA-GLUTAMYLCYSTEINE SYNTHETASE, LIPID-PEROXIDATION, ELECTROMAGNETIC-FIELD, ANTIOXIDANT ACTIVITY, GLUTATHIONE, BRAIN, ENHANCEMENT, PLASMA, SYSTEM
  • Gazi Üniversitesi Adresli: Evet

Özet

Continuous and intermittent 50 Hz, 1.5 mT magnetic field with the exposure period of 4 h/day for 4 days was used to investigate its possible effect on adult guinea pigs. Tissues and plasma specimens were assessed by biochemical parameters. Malondialdehyde (MDA), glutathione (GSH), nitric oxide (NO) levels and myeloperoxidase activity (MPO) were examined in plasma, liver and brain tissues. All parameters were determined by spectrophotometer. While intermittent magnetic field was effective on plasma lipid peroxidation, continuous magnetic field was found to be effective on plasma MPO activity and NO levels. Augmentation of lipid peroxidation was also observed in liver tissue both intermittent and continuous magnetic field exposures. These results indicate that both the intermittent and continuous magnetic field exposures affect various tissues in a distinct manner because of having different tissue antioxidant status and responses.