The machining centers are key resources for manufacturing companies in their dealing with their fierce competitive market environments. However, although selecting the most appropriate machining center is a very important decision for manufacturing companies, the availability of wide-range of types and models makes the selection process a complex and difficult task. In this study, a decision support system (DSS), namely MACSEL, is developed to help the decision makers in their machining center selection decisions. Several issues and applicability of the MACSEL is illustrated with case problems in the paper. Within the developed DSS, to select the feasible set of machining centers fifteen questions are placed in the elimination (pre-selection) module. The developed DSS uses fuzzy analytical hierarchy process (FAHP) or fuzzy technique for order preference by similarity to ideal solution (FTOPSIS), which are extended versions of multi-criteria decision making approaches, to rank the feasible machining centers. In the DSS, FAHP is used if a detailed pair-wise weighting of the hierarchically structured criteria is wanted. On the other hand, when a simpler separate weighting of each criterion is be considered as enough, FTOPSIS is used. (C) 2008 Elsevier Ltd. All rights reserved.