The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats


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Kip G., Turgut H. C., Alkan M., AYDIN M. E., Erbatur M. E., Kiraz H. A., ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.116, sa.12, ss.746-750, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Sayı: 12
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4149/bll_2015_146
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.746-750
  • Anahtar Kelimeler: sugammadex, streptozotocin, diabetes, renal damage, CAPILLARY ENDOTHELIAL FENESTRATION, INDUCED NEUROMUSCULAR BLOCKADE, STAGE RENAL-FAILURE, PODOCYTE DETACHMENT, ROCURONIUM, REVERSAL, SAFETY, MULTICENTER, EFFICACY
  • Gazi Üniversitesi Adresli: Evet

Özet

BACKGROUND: Sugammadex is primarily excreted via renal route. We investigated effects of low and high doses of sugammadex (16 mg/kg versus 96 mg/kg) on renal tissue samples of streptozotocin-induced diabetic rats.