A shift in the balance of regulatory T and T helper 17 cells in rheumatic heart disease.

Bas, Hatice; Baser, Kazim; Yavuz, Emine; Bolayir, Hasan; Yaman, Belma; ÜNLÜ, SERKAN; Cengel, Atiye; BAĞRIAÇIK, EMİN; Yalcin, MEHMET

doi:10.2310/jim.0000000000000023

A shift in the balance of regulatory T and T helper 17 cells in rheumatic heart disease.

Bas H. D., Baser K., Yavuz E., Bolayir H. A., Yaman B., ÜNLÜ S., ...Daha Fazla

Journal of investigative medicine : the official publication of the American Federation for Clinical Research, cilt.62, sa.1, ss.78-83, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 62 Sayı: 1
Basım Tarihi: 2014
Doi Numarası: 10.2310/jim.0000000000000023
Dergi Adı: Journal of investigative medicine : the official publication of the American Federation for Clinical Research
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.78-83
Anahtar Kelimeler: asthma, mice, prophylaxis, suplatast tosilate, treatment, C-REACTIVE PROTEIN, TGF-BETA, MONONUCLEAR-CELLS, VALVE DISEASE, DIFFERENTIATION, INFLAMMATION, TH17, LYMPHOCYTES, INDUCTION, RECOMMENDATIONS
Gazi Üniversitesi Adresli: Evet

Özet

Introduction Suplatast tosilate is a medication that inhibits T(H)2-type cytokines. We aimed to investigate the effects of suplatast tosilate treatment and prophylaxis on lung histopathology and cytokine levels in a mouse model of chronic asthma.