Anestezi Dergisi, cilt.17, sa.4, ss.205-210, 2009 (Scopus)
Objective: The aim of this study is to compare the effects of iv infusion affixed volume Lactated Ringer's solution (LR) or colloid (Voluven 6%) before spinal anesthesia with low dose ropivacaine p + opioid on the incidence of hypotension due to spinal anesthesia, amount of ephedrine used, maternal and neonatal parameters for elective cesarean deliveries. Methods: Sixty ASA II parturients scheduled to undergo elective cesarean section were randomly allocated to administer 1000 mL LR (n:30, group RL) or 500 mL colloid (Voluven 6%) (n:30, group V) before spinal anesthesia with ropivacaine+opioid. Both groups were compared in terms of the incidence of maternal hypotension, nausea and vomiting, amount of ephedrine used, sensory and motor block characteristics, first analgesic requirement, mobilization time and neonatal Apgar scores. Results: There were significant decreases in the mean blood pressure compared to control value after spinal anesthesia within each group. The incidence of hypotension (Group RL: 83.3 %, Group V: 80 %) and the amount of ephedrine used (Group RL: 28.5 ± 3.5 mg, Group V: 21.8 ± 3.4 mg) were similar. The incidence of nausea and vomiting, sensory and motor block characteristics, first analgesic requirement and Apgar scores were comparable. Conclusion: It has been demonstrated that fixed volume of either crsytalloid or colloid preloading similarly affected the incidence of hypotension due to spinal anesthesia with low dose ropivacaine + opioid, amount of ephedrine used, and other maternal and neonatal parameters during elective cesarean sections in the present study.